Posts Tagged ‘dysport’

Dysport Superior for Crow’s Feet Correction

Tuesday, June 21st, 2011

woman with eye wrinkles, crows feet, she may be candidate for dysportWhen targeted crow’s feet, Dysport achieves better results than Botox, according to a plastic surgeon who just published a study comparing the two botulinum toxin medications.

“Lateral orbital rhytids,” commonly called crow’s feet, are lines that travel horizontally from the eyes. Like other wrinkles, they develop gradually as a result of several factors including muscle contraction (especially squinting the eyes and moving the brow) and age-related loss of skin elasticity.

Botulinum toxin, as found in Dysport, is a product that temporarily stops facial muscle contractions to reduce or erase the appearance of wrinkles.

The comparative study was based on photographic evaluations of 90 adult patients who received Botox or Dysport injections in the crow’s feet wrinkles. As a “split-face” study, the drugs were injected on opposite sides of each patient’s face. Before and after photographs (during muscle contraction and at rest) were taken of each subject, grading their crow’s feet correction on a 5-point scale.

When patients evaluated the photos taken during muscle contraction, about two-thirds of them indicated a preference for the Dysport results. The difference was a full point higher on the wrinkle scale.

However, the authors mention several caveats about the Botox vs Dysport comparison for crow’s feet:

  • When subjects had relaxed faces (no significant muscle contraction), there was no visible difference between each product’s results.
  • Although they claim that Dysport treats crow’s feet more effectively, they can’t make any similar claims about treating wrinkles on the forehead or neck.
  • Allergan, maker of Botox, did not approve of the study methods, challenging their dosing ratio, study length and statistical analysis.
  • Medicis, maker of Dysport, provided funding for the study while Allergan declined to do so.

Although Dysport and Botox are similar in the way they correct wrinkles, the dosage is different. Both manufacturers caution that Botulinum toxin medications are “not interchangeable.” Therefore, if you’ve been treated with either product in the past, it is wise to notify your cosmetic surgeon before you decide to switch.

You can read about Dysport for crow’s feet in the latest online edition of Archives of Facial Plastic Surgery. A summary is also available from Healthday News.

Coastal Empire Plastic Surgery provides Dysport on Demand – No Appointment Necessary

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Botox or Facial Filler? How to Reduce Wrinkles Without Surgery

Thursday, April 28th, 2011

While Botox is the most popular cosmetic procedure in the world, with 5.4 million procedures performed last year in the United States alone, facial fillers have become very trendy in recent years. Products like Juvederm, Sculptra, and Artefill are continuing to redefine how we think about wrinkles. Each product has unique benefits that are worth considering.

All of these products work by being injected into the face over the course of about 15 minutes. The benefit of injectable treatments is that there is no downtime, as patients can usually return to their routine immediately after the procedure. Typically, the only side effects are what you might expect for an injection, such as redness, bruising, or stinging, which pass soon afterwards.

Botox is best suited to treating forehead lines, frown lines between the eyebrows, crow’s feet, lines between the upper lip and nose (perioral wrinkles), and wrinkles on the neck. All of these areas can be treated through targeted injections that relax certain muscles and allow others to pull the skin tighter than before.

Facial fillers are best used on smile lines and wrinkles below the mouth. However, they can often be used for other wrinkles and creases on the face, as well as for augmenting lips and filling out hollow cheeks.

Some fillers, such as Restylane, Elevess, Perlane, and Juvederm, use hyaluronic acid for striking results that last up to 6 months. All are highly effective on smile lines and other facial wrinkles, although each is formulated differently and suited to unique purposes. For example, Juvederm is especially well-suited to filling out lips, while Perlane contains no animal proteins whatsoever.

Other fillers last much longer than Botox and hyaluronic acid-based fillers. Sculptra lasts for up to two years and works by replacing lost collagen. Artefill, however, lasts longer than most (if not all) other facial fillers. It provides permanent support thanks to special microspheres that are injected along with the collagen and provide a framework for new collagen deposits. The microspheres are not absorbed into the skin, so that they may provide lasting support for a number of years.

Each product has unique benefits that are best suited to different patient needs, desires, and timeframes, so it’s always important to discuss your needs with a qualified plastic surgeon to find the injectable treatment that’s right for you.

New Botulinum Toxin Granted FDA Approval This Week

Tuesday, August 3rd, 2010

Merz Pharmaceuticals announced yesterday that FDA approval was granted for XEOMIN, a drug containing botulinum toxin.  The new drug is indicated for the treatment of cervical dystonia and blepharospasm.  Along with the relatively new Dysport and ubiquitous Botox®, Xeomin is the 3rd product of this kind to receive clearance in the U.S.

Two clinical trials were cited during the approval process, along with studies that compared XEOMIN to Botox®.  According to a study cited in the Journal of Neurological Sciences, [XEOMIN] showed “non-inferiority” to Botox® when used in equivalent doses for the treatment of blepharospasm.

The difference between XEOMIN and its competitors, according to the manufacturer Merz Pharmaceutical, is that “XEOMIN does not require refrigeration prior to reconstitution. “  The company says this could “simplify product distribution and storage, and help ensure product integrity at the time of injection.”

Merz is also acquiring Bioform Medical, a California company that manufactures Radiesse dermal filler.  The German company seems poised to create a significant presence in the U.S. aesthetics market.  When the acquisition of Bioform Medical is complete, the company will be rebranded “Merz Aesthetics.”

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